Differences

Difference Between Pinocytosis and Receptor Mediated Endocytosis

Pinocytosis refers to the ingestion of liquid into a cell by the budding of small vesicles from the cell membrane.

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This article writter by MN Editors on October 20, 2021

Microbiology Notes is an educational niche blog related to microbiology (bacteriology, virology, parasitology, mycology, immunology, molecular biology, biochemistry, etc.) and different branches of biology.

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Difference Between Pinocytosis and Receptor Mediated Endocytosis
Difference Between Pinocytosis and Receptor Mediated Endocytosis

Difference Between Pinocytosis and Receptor Mediated Endocytosis

  • The pinocytosis pathway involves cell drinking, where only fluids and dissolved nutrients are taken into a cell.
  • Cells used Receptor-mediated endocytosis process for selective internalization of specific molecules.
TopicPinocytosisReceptor Mediated Endocytosis
DefinitionPinocytosis refers to the ingestion of liquid into a cell by the budding of small vesicles from the cell membrane.The receptor-mediated endocytosis refers to an endocytotic mechanism in which specific molecules are ingested into the cell.
Also Known asPinocytosis is also knwon as cell drinkingThe receptor-mediated endocytosis is also known as clathrin-mediated endocytosis.
Components to be UptakenPinocytosis mainly uptakes liquids.Receptor-mediated endocytosis mainly uptakes solutes.
Receptor InvolvementThe receptors are not involved in pinocytosis.The receptors on the cell membrane do involve in receptor-mediated endocytosis.
SelectivityPinocytosis is not a selective process.Receptor-mediated endocytosis is a selective process.
Solute IntakeSolutes in the extracellular fluid enter into the cell through pinocytosis.Selected solutes bind to the receptors and enter the cell during receptor-mediated endocytosis.
Vesicle FormationVesicles form through the invagination of the plasma membrane.Vesicles form through the internal budding of the plasma membrane
EfficiencyPinocytosis is a less efficient processReceptor-mediated endocytosis is an efficient process.

Similarities of Pinocytosis and Receptor Mediated Endocytosis

  • Both of them are methods of endocytosis.
  • Both Pinocytosis and Receptor Mediated Endocytosis use the cell membrane for the process.
  • Both of them help in the uptake of proteins and other substances that cannot easily diffuse into the cell through the plasma membrane.
  • Both of them have a high demand for cellular energy and they are categorized under active transport methods.

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Microbiology Notes is an educational niche blog related to microbiology (bacteriology, virology, parasitology, mycology, immunology, molecular biology, biochemistry, etc.) and different branches of biology.

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