MCQ on Herpes simplex virus 1 (HSV-1)


Herpes simplex viruses (HSVs) are highly host-adapted viruses that can cause a variety of diseases in human hosts. (a) herpes simplex virus type 1 (HSV-1) and (b) herpes simplex virus type 2 (HSV-2) are the two forms of HSVs (HSV-2). Both types share DNA homology, antigenic determinants, tissue tropism, and illness symptoms, but their epidemiology is distinct. HSV-1 is transferred predominantly by contact with infected saliva, whereas HSV-2 is transmitted through sexual contact or vaginal tract infection from an infected mother to her newborn child.

MCQ on Herpes simplex virus 1 (HSV-1)

1. What is the causative agent of herpes labialis (cold sores)?

a. Herpes simplex virus 1 (HSV-1)


b. Herpes simplex virus 2 (HSV-2)

c. Varicella-zoster virus


d. Epstein-Barr virus

Answer: a

2. What is the main mode of transmission for HSV-1?


a. Sexual contact

b. Direct skin-to-skin contact


c. Airborne droplets

d. Contaminated food or drinks

Answer: b

3. Which of the following is a common symptom of primary HSV-1 infection?

a. Genital sores


b. Mouth sores

c. Eye redness and discharge

d. Rash and fever

Answer: b

4. Can HSV-1 be cured?

a. Yes, with antiviral medication

b. No, it is a lifelong infection

c. Yes, with proper hygiene

d. No, but symptoms can be manag

Answer: b

5. Which group of people is most at risk of HSV-1 infection?

a. Children

b. Elderly individuals

c. Healthcare workers

d. Women

Answer: a

6. Can HSV-1 be transmitted from mother to newborn during delivery?

a. Yes, if the mother has genital herpes

b. No, but it can be transmitted through breast milk

c. Yes, if the mother has oral herpes

d. No, HSV-1 cannot be transmitted from mother to newborn

Answer: c

7. Which of the following is a complication of HSV-1 infection in immunocompromised individuals?

a. Encephalitis

b. Pneumonia

c. Keratitis

d. All of the above

Answer: d

8. Can HSV-1 be transmitted through oral sex?

a. No

b. Yes

c. Only in certain cases

d. It depends on the individual’s immune system

Answer: b

9. What is the main drug used for treating recurrent herpes outbreaks?

a. Penicillin

b. Aciclovir

c. Erythromycin

d. Amoxicillin

Answer: b

10. Can HSV-1 cause genital herpes?

a. No, only HSV-2 can cause genital herpes

b. Yes, it is possible for HSV-1 to cause genital herpes

c. No, HSV-1 only causes oral herpes

d. Yes, but only in rare cases

Answer: b

11. How long can a person carry HSV-1 without showing symptoms?

a. Lifetime

b. A few weeks

c. A few months

d. It varies from person to person

Answer: a

12. Can HSV-1 be spread through sharing utensils or towels?

a. Yes, if the utensils or towels are contaminated with the virus

b. No, the virus cannot survive for long on surfaces

c. Yes, if the person has active herpes outbreaks

d. No, it is not possible to transmit HSV-1 through shared utensils or towels

Answer: a

13. Which of the following can trigger a herpes outbreak?

a. Stress

b. Illness

c. Hormonal changes

d. All of the above

Answer: b

14. Can a person get infected with HSV-1 more than once?

a. No, once infected the person is immune for life

b. Yes, a person can get infected multiple times

c. No, but reinfection is rare

d. Yes, but only if the person’s immune system is weakened

Answer: d

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