Skip to content
Microbiology Note
  • Notes
    • Biography
    • Botany
    • How To
    • Human Anatomy
    • Antimicrobial Drugs
    • Basic Microbiology
    • Biochemistry
    • Biology
    • Biosafety
    • Biotechnology
    • Cell Biology
    • Differences
    • Disease
    • Environmental Microbiology
    • Epidemiology
    • Food Microbiology
    • Genetics
    • Immunology
    • Industrial microbiology
    • Medical Microbiology
    • Microbiologists
    • Microscope
    • Molecular biology
    • Parasitology
    • Zoology
  • Biology Practicals
    • Biochemical Test
    • Culture Media
    • Cytopathology
    • Hematology
    • Immunology Practical
    • Instruments
    • Laboratory Tests
    • Microbiology Techniques
    • Practical Procedure
    • Protocols
    • Solution preparation
    • Staining
  • Microorganisms
    • Bacteriology
    • Mycology
    • Phycology
    • Prions
    • Protozoa
    • Virology
  • Others
    • Recommended Books
    • Research Methodology
    • Short type Questions
    • Syllabus
    • Top in Microbiology
    • Old Question Paper Download
    • Answer Key
      • BHU Answer Key
      • CSIR Net Answer Key
      • GATE Answer Key
      • IIT JAM BS Answer Key
      • IIT JAM BT Answer Key
  • Web Story
  • Tools
    • Amino Acid Chart
    • Atomic Mass Chart
    • Atomic Numbers Table
    • Bacteria Transformation Efficiency Calculator
    • Biochemical Test and Identification of different microorganisms
    • Boiling Point
    • Buffer Preparations and Recipes
    • Culture media Composition
    • Immunization Chart
    • pKa and pKb Table
    • Restriction Enzymes Cut Sites Table
    • Unit Converter
    • Water Solubility Table
Microbiology Note

Microbiology Note

  • Notes
    • Biography
    • Botany
    • How To
    • Human Anatomy
    • Antimicrobial Drugs
    • Basic Microbiology
    • Biochemistry
    • Biology
    • Biosafety
    • Biotechnology
    • Cell Biology
    • Differences
    • Disease
    • Environmental Microbiology
    • Epidemiology
    • Food Microbiology
    • Genetics
    • Immunology
    • Industrial microbiology
    • Medical Microbiology
    • Microbiologists
    • Microscope
    • Molecular biology
    • Parasitology
    • Zoology
  • Biology Practicals
    • Biochemical Test
    • Culture Media
    • Cytopathology
    • Hematology
    • Immunology Practical
    • Instruments
    • Laboratory Tests
    • Microbiology Techniques
    • Practical Procedure
    • Protocols
    • Solution preparation
    • Staining
  • Microorganisms
    • Bacteriology
    • Mycology
    • Phycology
    • Prions
    • Protozoa
    • Virology
  • Others
    • Recommended Books
    • Research Methodology
    • Short type Questions
    • Syllabus
    • Top in Microbiology
    • Old Question Paper Download
    • Answer Key
      • BHU Answer Key
      • CSIR Net Answer Key
      • GATE Answer Key
      • IIT JAM BS Answer Key
      • IIT JAM BT Answer Key
  • Web Story
  • Tools
    • Amino Acid Chart
    • Atomic Mass Chart
    • Atomic Numbers Table
    • Bacteria Transformation Efficiency Calculator
    • Biochemical Test and Identification of different microorganisms
    • Boiling Point
    • Buffer Preparations and Recipes
    • Culture media Composition
    • Immunization Chart
    • pKa and pKb Table
    • Restriction Enzymes Cut Sites Table
    • Unit Converter
    • Water Solubility Table

Prions

Prions are abnormal proteins that are believed to be responsible for several rare, degenerative brain disorders in animals and humans. These disorders, known as transmissible spongiform encephalopathies (TSEs), include mad cow disease in cows, scrapie in sheep, and Creutzfeldt-Jakob disease (CJD) in humans.

Prions are unusual in that they are infectious agents that do not contain nucleic acid, the genetic material found in all living organisms. Instead, they are thought to be composed solely of proteins. Prions are believed to cause TSEs by altering the shape and function of normal proteins in the brain. This leads to the accumulation of abnormal, proteinaceous aggregates in the brain, which can cause damage to brain tissue and lead to the symptoms of TSEs.

Prions are difficult to detect and eliminate, and there is currently no cure for TSEs. However, research into the biology of prions and TSEs is ongoing, and scientists are working to develop treatments and prevention strategies for these disorders.

TSEs are characterized by the accumulation of abnormal, proteinaceous aggregates in the brain, which can cause damage to brain tissue and lead to the symptoms of the disease.

Here are some examples of TSEs caused by prions:

  • Creutzfeldt-Jakob disease (CJD): CJD is a rare, degenerative brain disorder that affects humans. It is characterized by a rapid decline in mental function, personality changes, and involuntary movements. CJD is caused by abnormal prion proteins that accumulate in the brain.
  • Mad cow disease (bovine spongiform encephalopathy, BSE): BSE is a TSE that affects cows. It is characterized by abnormal behavior, difficulty standing and walking, and a loss of body weight. BSE is caused by abnormal prion proteins that accumulate in the brain.
  • Scrapie: Scrapie is a TSE that affects sheep. It is characterized by abnormal behavior, difficulty standing and walking, and a loss of body weight. Scrapie is caused by abnormal prion proteins that accumulate in the brain.
  • Chronic wasting disease (CWD): CWD is a TSE that affects deer, elk, and moose. It is characterized by abnormal behavior, difficulty standing and walking, and a loss of body weight. CWD is caused by abnormal prion proteins that accumulate in the brain.
  • Kuru: Kuru is a TSE that affects humans and is found primarily in the Fore people of Papua New Guinea. It is characterized by tremors, difficulty speaking and swallowing, and a loss of muscle control. Kuru is thought to be transmitted through the consumption of infected human brain tissue.

Overall, TSEs caused by prions are rare but serious diseases that can lead to significant brain damage and death. There is currently no cure for TSEs, and research into these diseases is ongoing.

Prions Disease: Definition, Structure, Prevention, Control, Treatment, Transmission.
MN Editors
In
Prions

Prions: Definition, Structure, Function, Disease, Prevention, Control, Treatment, Transmission.

What is Prions? Prion is an abnormal or misfolded protein that causes fatal disease in animals and humans by transmitting

January 22, 2022

Read Also

Streptococcus pneumoniae – Habitat, Morphology, Genomes

Culture Media Preparation, Maintenance and Preservation

Bead Homogenizer | Bead Mill Homogenizers – Principle, Uses

Rotor Stator Homogenizers – Definition, Principle, Parts, Uses

Applications of Fluorescence Spectroscopy

Fluorescence Spectrophotometry – Definition, Principle, Parts, Advantages, Uses

Bacteriological Examination of Waters by Using Membrane Filtration Method

Top 8 AI Generated Picture of Microscope

Top Universities in West Bengal Offering Microbiology

High Pressure Homogenizer – Principle, Types, Parts, Uses

Books

Top 6 Books For Biofertilizers and Biopesticides

Top and Best Books for Microbiology

Best and Top Books for Microbial Genetics and Molecular Biology

Best and Top Books for Genetic Engineering and Biotechnology

Best Books for Medical Microbiology and Immunology

Microbiologynote.com

Download our Microbiology Note app from play Store. Enjoy notes in your phone without ads. Download App

  • All Microbiology Notes
  • Amino Acid Chart
  • Atomic Mass Chart
  • Atomic Numbers Table
  • Bacteria Transformation Efficiency Calculator
  • Identification of different microorganisms
  • Boiling Point
  • Buffer Preparations and Recipes
  • Culture media Composition
  • Immunization Chart
  • Microbiology Quote
  • pKa and pKb Table
  • Restriction Enzymes Cut Sites Table
  • Unit Converter
  • Water Solubility Table
  • Web Story
  • Microbiology Jobs
Download Microbiology Note App
  • Privacy Policy
  • Contact Me
  • About Us
  • Advertise with us
  • Affiliate Disclosure
  • Cookie Policy
  • Disclaimer
2023 © Microbiologynote.com