Question

Who produced the first recombinant plasmid and introduced it into a bacterial host where it was replicated?

A. Baltimore and Temin

B. Cohen and Boyer

C. Jackson, Symons, and Berg

D. Arber and Smith

Answer 1

The correct answer is B. Cohen and Boyer. Stanley Cohen and Herbert Boyer are credited with producing the first recombinant plasmid and introducing it into a bacterial host for replication. In 1972, they successfully combined DNA fragments from different sources into a plasmid vector and introduced the recombinant plasmid into Escherichia coli bacteria. This groundbreaking achievement in genetic engineering laid the foundation for the development of recombinant DNA technology.