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Classical Pathway of Complement Activation

Classical Pathway of Complement Activation

Advertisements The classical pathway is a key immune system mechanism that plays an important role in defending the body from foreign invaders. It consists of a series of sequential interactions among complement components that result in the killing of target cells via a process known as cell lysis. The presence of an antibody attached to an … Read more

Biological Consequences of Complement Activation

Biological Consequences of Complement Activation

Through its role as a mediator, complement helps the humoral response become a potent defence mechanism that can eliminate pathogens. Other complement components or split products help with the inflammatory response, opsonization of antigen, virus neutralisation, and clearance of immune complexes in addition to the MAC’s role in mediating cell lysis. The binding of complement … Read more

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