Chemokines as well as cytokines constitute two immune modulating agents that are involved in mediating and modulating of the immune system’s responses. immune system. Different types of cytokine superfamilies are recognized: chemokines INFs, INFs, CSFs, TGFs and TNFs. They differ only by the function they perform within the body. Chemokines cause a gradient of concentration that directs other leukocytes to the location of the infection. The primary distinction between chemokines and cytokines is that cytokines are tiny proteins that are released by cells within the body that affect other cells. Chemokines are a part of the superfamily of cytokines and possess Chemotactic properties.