What are Superantigens (SAgs)? Advertisements Superantigens (SAgs) are a type of antigens that stimulate the immune system excessively. It specifically results in non-specific T-cell activation, polyclonal T-cell activation, and large cytokine release. Superantigens are microbial or viral toxins that constitute a class of disease-associated, immunostimulatory substances and function as V-restricted, highly potent polyclonal T cell … Read more