What is Transfer-messenger RNA (tmRNA)? Transfer-messenger RNA (tmRNA), also known as 10Sa or SsrA RNA, is exceptional among bifunctional RNAs in that it possesses both tRNA and mRNA characteristics. tmRNA employs these two activities to liberate translationally stalled ribosomes and to target nascent polypeptides for destruction. This coordinated reaction, known as trans-translation, helps to bacterial … Read more