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Routine Immunization For Children (Recommended By WHO)

AntigenAge of 1st DoseDoses in
Primary Series
Interval Between Doses
(1st to 2nd)
Interval Between Doses
(2nd to 3rd)
Interval Between Doses
(3rd to 4th)
Booster DoseConsiderations
BCGAs soon as possible after birth1Exceptions HIV
Hepatitis B (Option1)As soon as possible after birth (<24h)34 weeks (min) with
DTP1
4 weeks (min) with
DTP1
Premature and low birth weight
Co-administration and combination
vaccine
High risk groups
Hepatitis B (Option2)As soon as possible after birth (<24h)44 weeks (min) with
DTP1
4 weeks (min) with
DTP1
4 weeks (min),with
DTP3
Polio (OPV + IPV)6 weeks4
(IPV dose to
be given with
OPV dose from
14 weeks)
4 weeks (min) with
DTP2
4 weeks (min) with
DTP3
OPV birth dose
Transmission and importation risk
criteria
Polio (IPV / OPV Sequentia)8 weeks (IPV 1st)1-2 IPV
2 OPV
4-8 weeks4-8 weeks4-8 weeksOPV birth dose
Transmission and importation risk
criteria
Polio (IPV)8 weeks34-8 weeks4-8 weeksIPV booster needed for early schedule
(i.e. first dose given <8 weeks)
DTP6 weeks (min)34 weeks (min) – 8
weeks
4 weeks (min) – 8
weeks
1-6 years of
age
Delayed/ interrupted schedule
Combination vaccine
Haemophilus influenzae type b (Option1)6 weeks (min)
59 months (max)
34 weeks (min) with
DTP2
4 weeks (min) with
DTP3
Single dose if >12 months of age
Not recommended for children > 5 yrs
Delayed/ interrupted schedule
Co-administration and combination
vaccine
Haemophilus influenzae type b (Option2)6 weeks (min)
59 months (max)
2-38 weeks (min) if only 2 doses4 weeks (min) if 3 dose4 weeks (min) if 3
doses
At least 6
months (min)
after last dose
Single dose if >12 months of age
Not recommended for children > 5 yrs
Delayed/ interrupted schedule
Co-administration and combination
vaccine
Pneumococcal (Conjugate) (Option1)6 weeks (min)34 weeks (min)4 weeksVaccine optionsInitiate before 6 months of age
Co-administration HIV+ and preterm neonates booster
Pneumococcal (Conjugate) (Option2)6 weeks (min)28 weeks (min)9-15 monthsVaccine optionsInitiate before 6 months of age
Co-administration HIV+ and preterm neonates booster
Rotavirus (Rotarix)6 weeks (min) with DTP124 weeks (min) with
DTP2
Vaccine options
Not recommended if > 24 months old
Rotavirus (Rotarix Teq)6 weeks (min) with DTP134 weeks (min) – 10
weeks with DTP2
4 weeks (min) with
DTP3
Vaccine options
Not recommended if > 24 months old
Measles9 or 12 months
(6 months min)
24 weeks (min)Combination vaccine; HIV early
vaccination; Pregnancy
Rubella9 or 12 months with
measles containing vaccine
1Achieve and sustain 80% coverage
Combination vaccine and Co-
administration; Pregnancy
HPVAs soon as possible from 9
years of age
(females only)
26 months (min 5
months)
Target 9-13 year old girls
Pregnancy
Older age

15 years 3 doses
HIV and immunocompromised
Japanese Encephalitis6 months2 generally4 weeks (generally)Vaccine options and manufacturer’s
recommendations; Pregnancy; Immunocompromised
Japanese Encephalitis (Live attentuated)8 months1Vaccine options and manufacturer’s
recommendations; Pregnancy; Immunocompromised
Japanese Encephalitis (Live recombinant vaccine)9 months1Vaccine options and manufacturer’s
recommendations; Pregnancy; Immunocompromised
Yellow Fever9-12 months with measles
containing vaccine
1
Tick-Borne Encephalitis≥ 1 yr FSME-Immun and
Encepur
≥ 3 yrs TBE_Moscow and
EnceVir
11-3 months FSME-Immun
and Encepur
1-7 months TBE-Moscow
and EnceVir
5-12 months FSME-Immun and Encepur
12 months TBE-Moscow
and EnceVir
At least 1
Every 3 years
(see notes)
Definition of high-risk
Vaccine options
Timing of booster
Typhoid (Vi PS)2 years (min)1Every 3 yearsDefinition of high risk
Typhoid (Ty21a)Capsules 5 years (min)3 or 41 day1 day1 dayEvery 3-7 yearsDefinition of high risk
Cholera (Dukoral (WC-rBS))2 years (min)3 (2-5
years)
2 (≥6
years)
≥7 days (min) < 6
weeks (max)
≥7 days (min) < 6
weeks (max)
Every 6 months
Every 2 years
Minimum age
Definition of high risk
Cholera (Shanchol and
mORCVAX)
1 year (min)214 DaysAfter 2 yearsMinimum age
Definition of high risk
Meningococcal (MenA conjugate)9-18 months (5μg)1Definition of high risk; Vaccine
options;
2 doses if < 9 months with 8 week interval
Meningococcal (MenC conjugate)2-11 months28 WeeksAfter 1 yearDefinition of high risk; Vaccine options
Meningococcal (MenC conjugate)≥12 months1Definition of high risk; Vaccine options
Meningococcal (Quadrivalent conjugate)9-23 months212 WeeksDefinition of high risk; Vaccine options
Meningococcal (Quadrivalent conjugate)≥2 years1Definition of high risk; Vaccine options
Hepatitis A1 yearAt least 1Level of endemicity; Vaccine options;
Definition of high risk groups
RabiesAs required37 days14-21 daysDefinition of high risk, booster
Mumps12-18 months with measles containing vaccine21 month (min) to
school entry
Coverage criteria > 80%; Combo
vaccine
Seasonal influenza
(inactivated tri- and qudri-valent)
6 months (min)2 ( <9
years)
1 ( ≥ 9
years)
4 weeksRevaccinate
annually: 1
dose only
Priority risk groups, especially
pregnant women
Lower dosage for children 6-35
months
Varicella12-18 months4 weeks to 3 months
per manufacturer
recommendations
Achieve & sustain ≥ 80% coverage
Pregnancy
Co-admin with other live vaccines

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