Routine Immunization For Children (Recommended By WHO)
Antigen | Age of 1st Dose | Doses in Primary Series | Interval Between Doses (1st to 2nd) | Interval Between Doses (2nd to 3rd) | Interval Between Doses (3rd to 4th) | Booster Dose | Considerations |
BCG | As soon as possible after birth | 1 | Exceptions HIV | ||||
Hepatitis B (Option1) | As soon as possible after birth (<24h) | 3 | 4 weeks (min) with DTP1 | 4 weeks (min) with DTP1 | Premature and low birth weight Co-administration and combination vaccine High risk groups | ||
Hepatitis B (Option2) | As soon as possible after birth (<24h) | 4 | 4 weeks (min) with DTP1 | 4 weeks (min) with DTP1 | 4 weeks (min),with DTP3 | ||
Polio (OPV + IPV) | 6 weeks | 4 (IPV dose to be given with OPV dose from 14 weeks) | 4 weeks (min) with DTP2 | 4 weeks (min) with DTP3 | OPV birth dose Transmission and importation risk criteria | ||
Polio (IPV / OPV Sequentia) | 8 weeks (IPV 1st) | 1-2 IPV 2 OPV | 4-8 weeks | 4-8 weeks | 4-8 weeks | OPV birth dose Transmission and importation risk criteria | |
Polio (IPV) | 8 weeks | 3 | 4-8 weeks | 4-8 weeks | IPV booster needed for early schedule (i.e. first dose given <8 weeks) | ||
DTP | 6 weeks (min) | 3 | 4 weeks (min) – 8 weeks | 4 weeks (min) – 8 weeks | 1-6 years of age | Delayed/ interrupted schedule Combination vaccine | |
Haemophilus influenzae type b (Option1) | 6 weeks (min) 59 months (max) | 3 | 4 weeks (min) with DTP2 | 4 weeks (min) with DTP3 | Single dose if >12 months of age Not recommended for children > 5 yrs Delayed/ interrupted schedule Co-administration and combination vaccine | ||
Haemophilus influenzae type b (Option2) | 6 weeks (min) 59 months (max) | 2-3 | 8 weeks (min) if only 2 doses4 weeks (min) if 3 dose | 4 weeks (min) if 3 doses | At least 6 months (min) after last dose | Single dose if >12 months of age Not recommended for children > 5 yrs Delayed/ interrupted schedule Co-administration and combination vaccine | |
Pneumococcal (Conjugate) (Option1) | 6 weeks (min) | 3 | 4 weeks (min) | 4 weeks | Vaccine optionsInitiate before 6 months of age Co-administration HIV+ and preterm neonates booster | ||
Pneumococcal (Conjugate) (Option2) | 6 weeks (min) | 2 | 8 weeks (min) | 9-15 months | Vaccine optionsInitiate before 6 months of age Co-administration HIV+ and preterm neonates booster | ||
Rotavirus (Rotarix) | 6 weeks (min) with DTP1 | 2 | 4 weeks (min) with DTP2 | Vaccine options Not recommended if > 24 months old | |||
Rotavirus (Rotarix Teq) | 6 weeks (min) with DTP1 | 3 | 4 weeks (min) – 10 weeks with DTP2 | 4 weeks (min) with DTP3 | Vaccine options Not recommended if > 24 months old | ||
Measles | 9 or 12 months (6 months min) | 2 | 4 weeks (min) | Combination vaccine; HIV early vaccination; Pregnancy | |||
Rubella | 9 or 12 months with measles containing vaccine | 1 | Achieve and sustain 80% coverage Combination vaccine and Co- administration; Pregnancy | ||||
HPV | As soon as possible from 9 years of age (females only) | 2 | 6 months (min 5 months) | Target 9-13 year old girls Pregnancy Older age ≥ 15 years 3 doses HIV and immunocompromised | |||
Japanese Encephalitis | 6 months | 2 generally | 4 weeks (generally) | Vaccine options and manufacturer’s recommendations; Pregnancy; Immunocompromised | |||
Japanese Encephalitis (Live attentuated) | 8 months | 1 | Vaccine options and manufacturer’s recommendations; Pregnancy; Immunocompromised | ||||
Japanese Encephalitis (Live recombinant vaccine) | 9 months | 1 | Vaccine options and manufacturer’s recommendations; Pregnancy; Immunocompromised | ||||
Yellow Fever | 9-12 months with measles containing vaccine | 1 | |||||
Tick-Borne Encephalitis | ≥ 1 yr FSME-Immun and Encepur ≥ 3 yrs TBE_Moscow and EnceVir | 1 | 1-3 months FSME-Immun and Encepur 1-7 months TBE-Moscow and EnceVir | 5-12 months FSME-Immun and Encepur 12 months TBE-Moscow and EnceVir | At least 1 Every 3 years (see notes) | Definition of high-risk Vaccine options Timing of booster | |
Typhoid (Vi PS) | 2 years (min) | 1 | Every 3 years | Definition of high risk | |||
Typhoid (Ty21a) | Capsules 5 years (min) | 3 or 4 | 1 day | 1 day | 1 day | Every 3-7 years | Definition of high risk |
Cholera (Dukoral (WC-rBS)) | 2 years (min) | 3 (2-5 years) 2 (≥6 years) | ≥7 days (min) < 6 weeks (max) | ≥7 days (min) < 6 weeks (max) | Every 6 months Every 2 years | Minimum age Definition of high risk | |
Cholera (Shanchol and mORCVAX) | 1 year (min) | 2 | 14 Days | After 2 years | Minimum age Definition of high risk | ||
Meningococcal (MenA conjugate) | 9-18 months (5μg) | 1 | Definition of high risk; Vaccine options; 2 doses if < 9 months with 8 week interval | ||||
Meningococcal (MenC conjugate) | 2-11 months | 2 | 8 Weeks | After 1 year | Definition of high risk; Vaccine options | ||
Meningococcal (MenC conjugate) | ≥12 months | 1 | Definition of high risk; Vaccine options | ||||
Meningococcal (Quadrivalent conjugate) | 9-23 months | 2 | 12 Weeks | Definition of high risk; Vaccine options | |||
Meningococcal (Quadrivalent conjugate) | ≥2 years | 1 | Definition of high risk; Vaccine options | ||||
Hepatitis A | 1 year | At least 1 | Level of endemicity; Vaccine options; Definition of high risk groups | ||||
Rabies | As required | 3 | 7 days | 14-21 days | Definition of high risk, booster | ||
Mumps | 12-18 months with measles containing vaccine | 2 | 1 month (min) to school entry | Coverage criteria > 80%; Combo vaccine | |||
Seasonal influenza (inactivated tri- and qudri-valent) | 6 months (min) | 2 ( <9 years) 1 ( ≥ 9 years) | 4 weeks | Revaccinate annually: 1 dose only | Priority risk groups, especially pregnant women Lower dosage for children 6-35 months | ||
Varicella | 12-18 months | 4 weeks to 3 months per manufacturer recommendations | Achieve & sustain ≥ 80% coverage Pregnancy Co-admin with other live vaccines |