An Overview of Complement System What is Lectin Pathway of Complement Activation? Components of Lectin Pathway 1. Mannose-binding lectin Structural subunits of mannan-binding lectin (MBL) and ficolins 2. MBL serum levels and MBL2 gene polymorphisms 3. Ficolins Ficolin-1 Ficolin-2 Ficolin-3 4. MBL-associated serine proteases Steps, Mechanism, Process of Lectin Pathway Advertisements The lectin pathway, also … Read more
What is Alternative pathway of the complement system ? Activators of the alternative pathway Advertisements Activators of the alternative pathway of complement activation include Steps of activation of alternative pathway Four serum proteins comprise the initial component of the alternative pathway: C3b, factor B, factor D, and properdin. 1. C3bB complex Formation 2. C3bB Cleavage … Read more
Complement System Definition The complement system, also known as the complement cascade, is a component of the immune system that boosts the ability of antibodies and phagocytic cells to eliminate germs and damaged cells from an organism, stimulate inflammation, and assault the cell membrane of a pathogen. The complement system is an incredibly potent system … Read more
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