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Mendel’s Law of Segregation – Definition, Principle, Examples, Limitations

Mendel’s Law of Segregation Mindmap

What is Mendel’s Law of Segregation? Mendel’s Law of Segregation, a foundational principle in genetics, elucidates the behavior of alleles, the different forms of a gene, during the process of inheritance. Put simply, this law states that in the hybrids or heterozygotes of the first generation (F1 generation), when there are two contrasting characters – … Read more

Mendel’s Law of Dominance – Definition, Characteristics, Limitations, Examples

Mendel Law of Dominance

What is Mendel’s Law of Dominance? Mendel’s Law of Dominance is a fundamental principle in genetics that was derived from the experiments conducted by Gregor Mendel on pea plants. This law provides insights into how certain traits are expressed in offspring when two homozygous organisms with contrasting characters are crossed. Mendel’s Law of Dominance Explained: … Read more

Mendelian Inheritance & Mendelian Genetics – Definition, Experiment, Laws, Exceptions

Mendelian Inheritance - Definition, Experiment, Laws, Exceptions

What is Mendelian Inheritance? Mendel’s Experiment Gregor Mendel, the father of modern genetics, embarked on a series of pioneering breeding experiments between 1856 and 1863 with the intent of unraveling the intricate patterns of inheritance. He selected the common pea plant (Pisum sativum) as his experimental subject due to its various advantageous features: abundant variations … Read more

RNA – Definition, Structure, Types, Application

RNA - Definition, Structure, Types, Application

What is RNA? Definition of RNA RNA, or Ribonucleic acid, is a nucleic acid molecule that plays a crucial role in gene expression and protein synthesis. It is a single-stranded molecule composed of nucleotides, including adenine (A), cytosine (C), guanine (G), and uracil (U). RNA carries genetic information from DNA and acts as a template … Read more

RNA Splicing Definition, Types, Mechanisms

RNA Splicing Definition, Types, Mechanisms

What is RNA splicing? In order for mRNA to be translated into a protein, RNA splicing removes the intervening, non-coding sections of genes (introns) from pre-mRNA and links the protein-coding sequences (exons) together. Facts of RNA splicing What is Intron? What is Exon? What is Spliceosome? Types of Spliceosome There are two types of spliceosomes: … Read more

Plasmid Replication – Mechanism With Diagram

Plasmid Replication - Mechanism With Diagram

What are plasmids? In addition to the chromosome (nucleoid) of bacteria, the cytoplasm of bacterial cells typically contains genetic components. These genetic components live independently of the chromosome and proliferate as plasmids. or Plasmids are double-stranded, self-replicating DNA segments with a few kilobases that are often found in gram-negative and gram-positive bacterial strains, as well … Read more

Nucleoside – Definition, Types, Structure, Functions

Nucleoside - Definition, Types, Structure, Functions

What is Nucleoside? A nucleoside is a molecule composed of a pentose sugar linked to a nitrogenous base or glycosylamine. It can be considered as a nucleotide without a phosphate group. Nucleosides are essential components of DNA and RNA, playing a vital role in the storage and transmission of genetic information. In DNA, the nucleosides … Read more

Watson and Crick DNA Model

Watson and Crick Model of DNA

In 1953, James Watson and Francis Crick made a groundbreaking contribution to the understanding of DNA structure. By combining physical and chemical data, they proposed a model for DNA as a double helix, a twisted molecule consisting of two complementary strands held together by hydrogen bonds. This model revolutionized our knowledge of genetics and unlocked … Read more

What Is Gene Therapy? – Definition, Types, Vectors, Applications

What Is Gene Therapy? - Definition, Types, Vectors, Applications

Gene therapy is a groundbreaking field of medicine that focuses on the modification of cells to treat or prevent genetic disorders by repairing or replacing defective genetic material. It holds the potential to cure a wide range of genetic diseases by directly addressing the underlying genetic abnormalities. In this series of articles, we aim to … Read more

What Is Gene Silencing? – Definition, Process, Techniques, Applications

What Is Gene Silencing? - Definition, Process, Techniques, Applications

Gene silencing, a mechanism of reducing or suppressing gene expression, is critical in managing gene expression in cells. Genes, which are responsible for protein production, have distinct expression spectra that determine the amount of protein produced by a gene in a specific cell type. When the expression profile of genes is altered, however, it can … Read more

Gene Mapping – Definition, Types, Applications

Gene Mapping - Definition, Types, Applications

Gene mapping, also known as genome mapping or genome mapping, is an important technique used by scientists to establish the location of genes on a chromosome. It entails determining the location of a gene, quantifying the distance between genes, and establishing landmarks within the genome. Just like landmarks help us make our way around a … Read more

gab Operon – Definition, Structure, Regulation

gab Operon - Definition, Structure, Regulation

What is gab operon? The gab operon is in charge of turning -aminobutyrate (GABA) into succinate. The gab operon is made up of three structural genes: gabD, gabT, and gabP. These genes code for an enzyme called succinate semialdehyde dehydrogenase, an enzyme called GABA transaminase, and a protein called GABA permease. Downstream of the operon … Read more

Galactose (Gal) Operon – Structure, Regulation

Galactose (Gal) operon - Structure, Regulation

What is Gal operon? The gal operon is a bacterial operon that encodes galactose-metabolizing enzymes. This operon’s gene expression is repressed by the binding of repressor molecules to two operators. These repressors form a DNA loop by dimerizing. Loop and exteRNAl operator interference prohibit RNA polymerase from attaching to the promoter, hence preventing transcription. In … Read more

How  L-arabinose operon different from other operons?

How  L-arabinose operon different from other operons?

How  L-arabinose operon different from other operons? This operon is responsible for the cellular degradation of arabinose compounds. Arabinose is transformed to ribulose by arabinose isomerase, which is encoded by the araA gene, then phosphorylated by ribulokinase, which is encoded by the araB gene, and finally converted to xylulose-5-phosphate by ribulose-5-phosphate epimerase, which is encoded … Read more

Arabinose Operon – Definition, Structure, Mechanism 

Arabinose Operon - Definition, Structure, Mechanism 

What is Arabinose Operon? The L-arabinose operon, also known as the ara or araBAD operon, is essential for the degradation of the five-carbon sugar L-arabinose in Escherichia coli. The L-arabinose operon contains three structural genes: araB, araA, and araD (together referred to as araBAD), which code for three metabolic enzymes essential for L-arabinose metabolism. These … Read more

Tryptophan (Trp) Operon –  Repressible operon

Tryptophan (Trp) Operon -  Repressible operon

Tryptophan (Trp) Operon Definition A collection of genes that are transcribed together encode the components for tryptophan synthesis. Note: The trp operon is a set of genes that, when transcribed together, encode the enzymes that cause bacteria to generate the amino acid tryptophan. The trp operon was initially defined in Escherichia coli, and it has … Read more

Lac Operon (lactose operon) – Definition, Structure, Mechanisms

Lac Operon - Definition, Structure, Mechanisms

What is lac Operon? Jacques Monod (1910–1976) began studying bacterial growth and regulation in the late 1930s. He selected E. coli as a model bacteria and eventually concentrated on genes involved in E. coli’s growth on lactose. Francois Jacob joined him in his studies roughly 15 years later (1920–2013). As a result of their research, … Read more

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